The antioxidant effect of natural polyphenolic complexes of grape wine in the rat kidneys under streptozotocin-induced diabetes mellitus

A. Gnatush, V. Drel, N. Sybirna

Ivan Franko National University of Lviv
4, Hryshevskyi St., Lviv 79005, Ukraine

The possible protective effect of the speciment of natural polyphenols complexes of grape wine in the kidneys of white rats under streptozotocin-induced diabetes mellitus, which is reflected in the activation of enzyme antioxidant system and reduced pathogenic actions of reactive oxygen species underlying the mechanisms of various diabetic diseases, separately diabetic nephropathy is discussed in this scientific article.

Keywords: diabetes mellitus, polyphenolic complexes, diabetes nephropathy, oxidative stress, antioxidant protection

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