Antimicrobial activity of ethanol extract of the Hyssopus officinalis L. (Lamiaceae)

L. Kotyuk1, D. Rakhmetov2

1 Zhytomyr National Agroecological University
7, Stary Boulevard, Zhytomyr 10008, Ukraine
2 M.M. Gryshko National Botanical Garden, NAS of Ukraine
1, Timiryazevska St., Kyiv 01014, Ukraine

The paper investigates the biological activity of 40% ethanol extract of Hyssopus officinalis, herb grown under the conditions of Ukrainian Polissya as to Escherichia coli –906 (ATCC 25922); Staphylococcus aureus –904 (ATCC 25923); Pseudomonas aeruginosa –900 (ATCC 9027) and Candida albicans Y1918 (ATCC 885653), which are pathogenic in reference to other organisms. The ethanol extract of H. officinalis contained substances that influenced S. aureus and E. coli causing the twofold increase of MBC indices of 40% ethyl alcohol. The extracted substances did not influence P. aeruginosa and C. albicans. The paper provides the information on the component composition of ethereal oil of Hyssopus officinalis cultivated in Zhytomyr Polissya. In the ethereal oil of mint anise 30 component were identified: isopinocamphone (44,43%), pinocamphone (35,49%), mirtenol (5,26%), germacren D (3,15%), (2,93%), byciclogermacrene (1,35%), β-pinene (0,97%) and other. The paper draws attention to the prospects of the further more detailed study of ethanol extracts of hyssop with the aim of producing antibacterial herbal preparations.

Keywords: Hyssopus officinalis L., ethanol extract, minimal bacteriostatic concentration, minimal bactericidal concentration

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