Association of single nucleotide polymorphism (SNP) rs 2235186 of gene MAO-A with the level of agression and empathy among residents of the city Kharkiv

K. Luchko

V.N.Karazin National University of Kharkiv
4, Svobody Sq., Kharkiv 61022, Ukraine
ekaterina_luchko@mail.ru

One hundred married couples residents of Kharkiv have been tested for the level of aggression (Assingers test) and empathy (MehrabianEpstein test) and undergone genetic typing by SNPrs2235186-linked gene of monoamine oxidase -, a substitute for /. In men, the average values of the aggression index are higher, and the empathy index is lower than in women.Ѡ(=0,58) is the major allele in Kharkov population. Its frequency in the sample of women is 0,56, in the sample of men 0,61. In men with genotype , the average level of aggression is x=36,5 points (CI=35,837,2), for genotype the value is higher x=39,9 points (CI=39,340,5). By the level of empathy, men with genotype (x=6,0 (CI=5,56,5)) dominate over men with genotype (x=4,3 points). In homozygous women, the average indices of aggression are: with genotype Ѡ 34,8 points (CI=33,935,7), with genotype Ҡ 38,8 points (CI=37,640,0). For the level of empathy, these values are:Ѡ 6,4 points (CI=5,87,0),Ҡ 5,6 (CI=4,86,4). In heterozygous women (), these indices have an intermediate value: the average level of aggression is 36,7 points (CI=36,037,4), that of empathy 5,3 points (CI=4,85,8). There is positive marital assortativity for the said genotypes, expressed by more frequent representation of ×Ѡand× couples, and scarcer representation of ×Ҡand×Ѡcouples than with panmixia.


Keywords: marital structure, aggression, empathy, correlation, SNP rs2235186 -


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